Information & Guiding Principles

 

Guided Psilocybin Truffle Sessions for Personal Development
Offered by Resolve Collective B.V.
Chamber of Commerce: 96541245
VAT: NL867653553B01
Version: March 2026


 

Welcome

This document is intended to help you make a well-informed decision about participating in a guided psilocybin truffle session. It outlines what you can expect, the potential risks involved, and how we aim to support your safety throughout the process.

You will find information about:

  • The nature and effects of psilocybin truffles

  • What a guided session involves

  • Safety considerations and potential risks

  • Situations in which participation is not appropriate

  • How we support your safety and well-being

  • Your responsibilities as a participant

Please read this document carefully and take note of any questions you may have. These can be discussed during your intake conversation. Your safety and well-being are our primary concern.


 

1. Core Principles

What this is — and what it is not

A guided psilocybin session is intended to support personal development, self-exploration, and introspection.

It is not:

  • Medical treatment

  • Psychotherapy in a clinical sense

  • Healthcare as defined under the Dutch Medical Treatment Contracts Act (WGBO)

Instead, it is:

  • A structured, guided experience aimed at personal insight and growth

  • A supportive setting for inward exploration

  • A voluntary process undertaken at your own responsibility


No medical care

The guidance provided by Resolve Collective does not constitute medical or psychiatric care.

This means that:

  • No diagnoses are made

  • No treatment plans are created

  • No medical advice is given

  • No guidance is provided on starting, stopping, or adjusting medication

If there is any doubt about your physical or mental health, you will be referred to your general practitioner or treating physician. In such cases, participation will not proceed.

Our role is to support a personal, introspective experience within a harm reduction framework.


Definitions

  • Session: the guided experience involving psilocybin truffles

  • Integration: one or more follow-up conversations after the session

  • Facilitators: trained guides supporting the session

  • Participant: the individual taking part in a private, non-professional capacity


Harm reduction

The use of psilocybin carries inherent risks. Our approach is based on harm reduction: minimizing potential risks while acknowledging that they cannot be fully eliminated.

We support safety through:

  • Careful screening prior to participation

  • Professional guidance throughout the process

  • A calm, controlled environment

  • Preparation and integration support

  • A clear protocol for emergencies


 

2. What are psilocybin truffles?

Psilocybin truffles contain psilocybin, a naturally occurring compound that temporarily alters perception, mood, and cognition. In the body, psilocybin is converted into psilocin, which interacts with serotonin receptors in the brain.

Possible effects include:

  • Altered sensory perception (e.g. colors, sounds, patterns)

  • Heightened emotional sensitivity

  • Changes in the perception of time

  • Deep introspective insights

  • Experiences that may feel meaningful or, for some, spiritual in nature

Effects typically begin within 20 to 60 minutes and last approximately 4 to 6 hours.


 

3. Legal status in the Netherlands

Psilocybin truffles (also known as “magic truffles” or sclerotia) are legal in the Netherlands when sold and used in their fresh, unprocessed form. This differs from psilocybin mushrooms, which have been prohibited since 2008.

This legal status applies to the substance itself and does not define or regulate the context in which it is used.


 

4. Important safety information

Your safety is central to our work. Before participating, your physical and psychological suitability will be carefully assessed.


4.1 When participation is not appropriate

You cannot participate if you:

  • Have (or have had) a psychiatric condition such as:

    • Psychosis or schizophrenia

    • Bipolar disorder

    • Severe personality disorders involving impaired reality testing

    • Suicidal thoughts or tendencies

  • Have a first-degree relative with a psychotic disorder

  • Have cardiovascular conditions such as:

    • Untreated high blood pressure

    • Heart rhythm disorders

    • A history of heart attack or stroke

  • Are pregnant or breastfeeding

  • Are using medications that may interact with psilocybin

These criteria are in place to reduce risk and protect your well-being.


4.2 Medication and interactions

Psilocybin may interact unpredictably with certain medications.

Participation is not possible if you are using:

  • SSRIs or SNRIs (commonly prescribed for depression or anxiety)

  • MAO inhibitors

  • Antipsychotic medication

  • Lithium

In rare cases, participation may be considered if your prescribing physician confirms in writing that temporary discontinuation is medically safe. We do not advise making any changes to medication independently.

The use of alcohol or other psychoactive substances around the time of the session is strongly discouraged.


4.3 Potential risks

Research suggests that psilocybin has a relatively low risk profile compared to many other psychoactive substances, particularly in controlled and supported environments. However, risks do exist.

Psychological effects

Common:

  • Anxiety or emotional discomfort

  • Periods of fear or panic

  • Challenging or overwhelming experiences

  • Confrontation with difficult memories or emotions

Less common:

  • Paranoia

  • Temporary confusion or distorted beliefs

  • Feelings of disconnection from self or surroundings

  • Dissociation or trauma-related imagery

These experiences are usually temporary and subside as the effects wear off. With appropriate support, even difficult experiences can contribute to meaningful insight.


Physical effects

Common:

  • Headache

  • Temporary increase in heart rate and blood pressure

  • Nausea

Less common:

  • Reduced coordination

  • Tingling sensations

  • Chills or drowsiness

  • Mild confusion

Serious physical complications are rare, especially in guided settings, but cannot be entirely ruled out.


Longer-term risks (rare)

  • Temporary visual disturbances after the session (HPPD)

  • Persistent psychological distress

  • Worsening of underlying mental health vulnerabilities

These risks are primarily associated with pre-existing conditions or use outside a safe, structured setting.

Psilocybin is not physically addictive and is not known to cause long-term organ damage.


Dosage

Higher doses increase the likelihood of challenging experiences. Dosage is determined carefully in consultation with you, based on your experience, intention, and overall condition.


 

5. How we support your safety

Screening

We conduct a thorough intake process covering:

  • Physical and mental health

  • Medical and psychiatric history

  • Medication use

  • Family history

  • Previous experience with psychedelics

  • Your intentions and expectations


Preparation

Preparation focuses on:

  • Building trust and psychological safety

  • Clarifying your intention

  • Setting realistic expectations

  • Learning how to navigate challenging moments

  • Understanding available support


During the session

  • A calm, comfortable, and contained environment

  • Continuous presence of a facilitator

  • Non-directive guidance

  • Support during difficult experiences

  • A non-judgmental atmosphere


Integration

After the session, we support you in:

  • Making sense of your experience

  • Integrating insights into daily life

  • Processing emotions

  • Identifying next steps


Emergency protocol

In the event of a medical emergency:

  • Emergency services will be contacted

  • Basic first aid will be provided

  • Relevant information will be shared with responders

  • The incident will be documented


 

6. Your responsibilities

Your safety depends in part on your openness and cooperation.

You are expected to be fully transparent about:

  • Your physical and mental health

  • Medical and psychiatric history

  • Medication and supplement use

  • Substance use (past and present)

Incomplete or inaccurate information may increase risk and may lead to exclusion from participation.


Voluntary participation

Participation is entirely voluntary. You are free to withdraw at any time.


Aftercare

After the session:

  • Arrange safe transport home

  • Do not drive or operate machinery for 24 hours

  • Reach out if you experience unexpected effects

  • Participate in integration sessions


 

7. Frequently asked questions

Is this safe?
In a well-prepared and guided setting, risks are significantly reduced, though not eliminated.

Is psilocybin addictive?
No, it does not lead to physical dependence and has a very low potential for misuse.

What if I have a difficult experience?
Facilitators are trained to support you. Challenging moments are not uncommon and can be meaningful when properly integrated.

How long do the effects last?
Typically 4 to 6 hours, with possible lingering fatigue afterward. Psychological effects may persist longer.

Can I combine this with antidepressants?
No, unless explicitly approved by your prescribing physician.

Do I need to be spiritual?
No. The experience can be approached from psychological, philosophical, or personal perspectives.


 

8. Scientific background

This document is informed by contemporary research and harm reduction guidelines from institutions such as the Trimbos Institute, the Dutch Psychiatric Association (NVvP), and international research centers including Johns Hopkins University and Imperial College London.

A full list of references is listed here [click here].

 


 

9. Contact

If you have questions after reading this document, please bring them to your intake or preparation sessions. Open dialogue is essential.

Resolve Collective B.V.
Keizersgracht 394
1016 GB Amsterdam

Evelien Hekkelman: +31 6 21892633
Femke Mureau: +31 6 55355039


 

Next steps

If you are considering participation:

  • You will first complete an intake screening

  • If suitable, you will sign an informed consent form

  • Preparation sessions will be scheduled

  • Your session will be planned accordingly

Take the time you need. Participation should only proceed when you feel fully informed and comfortable with your decision.


This document is for informational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider if you have concerns about your health.